A 5 Meps $100 USB2.0 Address-Event Monitor-Sequencer Interface

This paper describes a high-speed USB2.0 address-event representation (AER) interface that allows simultaneous monitoring and sequencing of precisely timed AER data. This low-cost (<$100), two chip, bus powered interface can achieve sustained AER event rates of 5 megaevents per second (Meps). Several boards can be electrically synchronized, allowing simultaneous synchronized capture from multiple devices. It has three parallel AER ports, one for sequencing, one for monitoring and one for passing through the monitored events. This paper also describes the host software infrastructure that makes the board usable for a heterogeneous mixture of AER devices and that allows recording and playback of recorded data

Análisis de la motivación al cambio en sujetos que han seguido un programa formativo en violencia doméstica

En los últimos años, se ha hecho patente el interés de los órganos legislativos y judiciales por dar respuesta a la problemática existente en el ámbito de la violencia familiar. Las partes implicadas directamente en el conflicto (agresor y víctima) han constituido el principal foco de intervención e investigación. En cuanto a los agresores, se han destinado numerosos esfuerzos a la identificación de las principales características sociodemográficas y criminales, se han explorado diferentes perfiles en función de los rasgos de personalidad o psicopatológicos más relevantes, se han diseñado numerosas intervenciones terapéuticas, etc. En cuanto a las medidas judiciales que pueden imponerse en los casos de violencia contra la pareja, las medidas penales alternativas son unas de las más relevantes en la actualidad. Dentro del abanico de medidas penales alternativas, existen los programas específicos de reeducación y/o tratamiento psicológico (PF). Estas intervenciones pretenden proporcionar una serie de elementos facilitadores para la reinserción del infractor en la comunidad. Pero, para lograr este objetivo, es necesario que se produzca en el individuo un proceso complejo llamado cambio terapéutico, para el que la mayoría de los autores consideran que es necesaria una fuerte motivación por parte del individuo

La motivación al cambio de los agresores de pareja que realizan un programa formativo: Diseño de un Plan de Intervención Motivacional (PIM)

En la actualidad, el número de medidas penales alternativas de Programa Formativo en materia de violencia doméstica que se imponen en Cataluña es muy elevado. Estos programas son interven-ciones específicas de reeducación y/o tratamiento psicológico que se encaminan a movilizar en el usuario una serie de cambios cognitivos, actitudinales, emocionales y conductuales. Estos cambios y conocimientos se dirigen a facilitar la reinserción del individuo en la comunidad y a prevenir la co-misión de nuevos comportamientos violentos. Los principales elementos presentes en las intervenciones y programas psicológicos eficaces han sido ampliamente identificados por la bibliografía internacional: evaluación del riesgo de los individuos, identificación de sus necesidades criminogénicas, objetivos orientados a estas necesidades, focali-zación de los programas en la enseñanza de habilidades de vida y reestructuración del pensamiento, adaptación de las intervenciones a las características de los individuos, potenciación de la motiva-ción por el cambio, etc. A pesar de ello, hasta el momento, los programas formativos en materia de violencia doméstica han demostrado un nivel de eficacia entre moderado y reducido

Diagnostic and Therapeutic Algorithm for Appendiceal Tumors and Pseudomyxoma Peritonei: A Consensus of the Peritoneal Malignancies Oncoteam of the Italian Society of Surgical Oncology (SICO)

Aim: Pseudomyxoma peritonei (PMP) is an uncommon pathology, and its rarity causes a lack of scientific evidence, precluding the design of a prospective trial. A diagnostic and therapeutic algorithm (DTA) is necessary in order to standardize the disease treatment while balancing optimal patient management and the correct use of resources. The Consensus of the Italian Society of Surgical Oncology (SICO) Oncoteam aims at defining a diagnostic and therapeutic pathway for PMP and appendiceal primary tumors applicable in Italian healthcare. Method: The consensus panel included 10 delegated representatives of oncological referral centers for Peritoneal Surface Malignancies (PSM) affiliated to the SICO PSM Oncoteam. A list of statements regarding the DTA of patients with PMP was prepared according to recommendations based on the review of the literature and expert opinion. Results: A consensus was obtained on 33 of the 34 statements linked to the DTA; two flowcharts regarding the management of primary appendiceal cancer and peritoneal disease were approved. Conclusion: Currently, consensus has been reached on pathological classification, preoperative evaluation, cytoreductive surgery technical detail, and systemic treatment; some controversies still exist regarding the exclusion criteria for HIPEC treatment. A shared Italian model of DTA is an essential tool to ensure the appropriateness and equity of treatment for these patients

Multidataset Incremental Training for Optic Disc Segmentation

When convolutional neural networks are applied to image segmentation results depend greatly on the data sets used to train the networks. Cloud providers support multi GPU and TPU virtual machines making the idea of cloud-based segmentation as service attractive. In this paper we study the problem of building a segmentation service, where images would come from different acquisition instruments, by training a generalized U-Net with images from a single or several datasets. We also study the possibility of training with a single instrument and perform quick retrains when more data is available. As our example we perform segmentation of Optic Disc in fundus images which is useful for glau coma diagnosis. We use two publicly available data sets (RIM-One V3, DRISHTI) for individual, mixed or incremental training. We show that multidataset or incremental training can produce results that are simi lar to those published by researchers who use the same dataset for both training and validation

Using population-based data to evaluate the impact of adherence to endocrine therapy on survival in breast cancer through the web-application BreCanSurvPred

We show how the use and interpretation of population-based cancer survival indicators can help oncologists talk with breast cancer (BC) patients about the relationship between their prognosis and their adherence to endocrine therapy (ET). The study population comprised a population-based cohort of estrogen receptor positive BC patients (N = 1268) diagnosed in Girona and Tarragona (Northeastern Spain) and classified according to HER2 status (+ / -), stage at diagnosis (I/II/III) and five-year cumulative adherence rate (adherent > 80%; non-adherent <= 80%). Cox regression analysis was performed to identify significant prognostic factors for overall survival, whereas relative survival (RS) was used to estimate the crude probability of death due to BC (PBC). Stage and adherence to ET were the significant factors for predicting all-cause mortality. Compared to stage I, risk of death increased in stage II (hazard ratio [HR] 2.24, 95% confidence interval [CI]: 1.51-3.30) and stage III (HR 5.11, 95% CI 3.46-7.51), and it decreased with adherence to ET (HR 0.57, 95% CI 0.41-0.59). PBC differences were higher in non-adherent patients compared to adherent ones and increased across stages: stage I: 6.61% (95% CI 0.05-13.20); stage II: 9.77% (95% CI 0.59-19.01), and stage III: 22.31% (95% CI 6.34-38.45). The age-adjusted survival curves derived from this modeling were implemented in the web application BreCanSurvPred (https://pdocomputation.snpstats.net/BreCanSurvPred). Web applications like BreCanSurvPred can help oncologists discuss the consequences of non-adherence to prescribed ET with patients

Evaluation of manure management systems in Europe

The gross value of the agricultural goods in 2014 amounted up to 370 billion Euros. Almost 50% of all agricultural production is provided by livestock farming.Postprint (published version

Fragmentation of Contaminant and Endogenous DNA in Ancient Samples Determined by Shotgun Sequencing; Prospects for Human Palaeogenomics

Despite the successful retrieval of genomes from past remains, the prospects for human palaeogenomics remain unclear because of the difficulty of distinguishing contaminant from endogenous DNA sequences. Previous sequence data generated on high-throughput sequencing platforms indicate that fragmentation of ancient DNA sequences is a characteristic trait primarily arising due to depurination processes that create abasic sites leading to DNA breaks